January 21st,
2025, East Setauket, NY – NutraShure Distribution, LLC. (“NutraShure”),
a premium ingredient supplier in the dietary supplement and functional food and
beverage categories shared today its groundbreaking study published in the Journal
of Exercise and Nutrition: A Pharmacokinetic Comparison of Three Butyrate
Products. The study provides new insights into the pharmacokinetics and
physiological effects of three butyrate forms – sodium butyrate (NaB), lysine
butyrate (as BIOMEnd™) (LysB), and tributyrin (TB).
The study included healthy adult men, aged
25-45, who ingested one of three butyrate forms, with blood samples and
assessments collected over a 3.5-hour post-ingestion period. Measurements
included serum butyrate concentrations, feelings of well-being, and
physiological vitals. Blood samples were collected at six time points and
analyzed using advanced GC-MS techniques to measure serum butyrate levels. In addition,
Visual Analog Scales (VAS) evaluated participants’ well-being, mood,
motivation, and concentration at multiple time points.
The
results showed BIOMEnd, a STACK3D top innovation of 2024, had significantly
higher peak plasma concentrations (Cmax) and quicker time to maximum
concentration (Tmax) compared to tributyrin – indicating its superior
bioavailability and faster systemic circulation. In addition, participants
reported improved feelings of well-being, calmness, and motivation after
ingesting BIOMEnd. Notably, BIOMEnd achieved 500% greater Cmax than tributyrin
and 180% greater Cmax than sodium butyrate.
The results emphasize BIOMEnd’s efficacy in delivering butyrate into the
bloodstream more effectively than current forms on the market.
“This
study is the first comparative study of three commercially available forms of
butyrate,” said Brandon Sojka, CEO at NutraShure. “The exceptional
pharmacokinetic advantage of BIOMEnd coupled with our new substantiated GLP-1
claims and superior delivery form allows us to provide a truly innovative
solution for supporting gut health, weight management, and overall well-being.”
BIOMEnd is
a superior form of butyrate, delivering benefits to solve ongoing palatability
and solubility issues seen with traditional butyrate ingredients currently on
the market. Designed with both formulators and
consumers in mind, BIOMEnd delivers superior benefits for gut health, GLP-1
support, and immune health without the unpleasant taste often associated with
other butyrate products on the market.
About NutraShure
Distribution, LLC.
NutraShure
Distribution, LLC. is a premium ingredient supplier for use in dietary
supplements, functional foods, and beverages. NutraShure set out with the goal
of optimizing human performance and increasing the overall quality of daily
life. NutraShure Distribution offers ingredients with a wide range of health benefit
categories with patent-protected IP and preclinical and clinical research. These
categories include sports nutrition, men’s health, gut health, weight
management, immune health, and more.
